Leberspezifisches Kontrastmittel MRT

KMLeberMrt

Table 1. Characteristics of Gadolinium-based Contrast Agents

Name Trade Name Structure Type
Gadodiamide Omniscan® Linear nonionic Extracellular
Gadoversetamide OptiMARK® Linear nonionic Extracellular
Gadopentetate dimeglumine Magnevist® Linear ionic Extracellular
Gadobenate dimeglumine MultiHance® Linear ionic Hepatobiliary
Gadoxetate disodium Eovist®/Primovist® Linear ionic Hepatobiliary
Gadofosveset trisodium Ablavar®/Vasovist® Linear ionic Blood pool
Gadobutrol Gadovist® Macrocyclic nonionic Extracellular
Gadoteridol ProHance® Macrocyclic nonionic Extracellular
Gadoterate meglumine Dotarem® Macrocyclic ionic Extracellular
Name Log
K therm
Log
K cond 7.4
Elimination Pathway ACR Classification
Gadodiamide 16.8 14.9 Kidney Group I
Gadoversetamide 16.6 15.0 Kidney Group I
Gadopentetate dimeglumine 22.1 17.7 Kidney Group I
Gadobenate dimeglumine 22.6 18.4 93% kidney, 3% bile Group II
Gadoxetate disodium 23.5 18.7 50% kidney, 50% bile Group III
Gadofosveset trisodium 22.0 18.9 91% kidney, 9% bile Group III
Gadobutrol 21.8 15.5 Kidney Group II
Gadoteridol 22.8 17.1 Kidney Group II
Gadoterate meglumine 25.4 19.0 Kidney Group II

 

http://img.medscape.com/article/842/629/842629-fig15.jpg

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